2012 Program

To download the final conference booklet click here

Thursday, 28th June 2012

 9:30 - 10:35am SESSION 1: Welcome and first plenary                                   

 Moderator: Darren Jones


Welcome and Introduction from Conference Sponsor Cellmid Limited Maria Halasz, CEO, Cellmid Ltd, Sydney, Australia

 9:35am-9:45am Welcome from Conference Hosts Prof. Dr. Ayhan Bilir Department of Histology and Embryology, Faculty of Medicine, Istanbul University, Turkey Assoc Prof Mine Erguven, Department of Biochemistry, Faculty of Medicine, Yeni Yüzyıl University, Istanbul, Turkey Prof Yunus Söylet, Rector, Istanbul University Prof İzzet Bozkurt, Rector, Yeni Yüzyıl University

PLENARY 1: Midkine: From Sydney to Istanbul Prof Takashi Muramatsu, Faculty of Psychological and Physical Science, Aichi Gakuin University, Aichi, Japan


Morning tea and poster viewing

 11:00am-12:45pm SESSION 2: MK, Inflammation and immune system regulation                                                

 Moderator: Takashi Muramatsu


Midkine and its receptor RPTP regulate B cell survival in a pathway induced by CD74 Assoc Prof Idit Shachar, Department of Immunology, Weizmann Institute of Sciences, Rehovot, Israel

 11:30am -12:00pm Midkine as a surrogate marker in chronic inflammatory diseases Prof Emeritus Robert Clancy, University of Newcastle and Hunter Area Pathology Service, Newcastle, Australia
 12:00pm-12:30pm Midkine and  anti-mullerian hormone Assoc Prof Mine Erguven, Department of Biochemistry, Faculty of Medicine, Yeni Yüzyıl University, Istanbul, Turkey

 12:30pm-12:45pm BOOK LAUNCH:   

 Moderator: Kathrin Guenther
 12:30pm-12:45pm Midkine: From Embryogenesis to Pathogenesis and Therapy. Springer, 2012 Assoc. Prof. Dr. Mine Ergüven, Prof. Dr. Takashi Muramatsu, Prof. Dr. Ayhan Bilir



 12:45pm-1:45pm SESSION 3: MK in vertebrate development                                                                 

 Moderator: Gonzalo Herradon


An in-vivo structure-function analysis of midkine using the zebrafish model Assoc Prof Christoph Winkler, Dept. of Biological Sciences, National University of Singapore

 2:15pm-2:45pm Midkine-A functions upstream of ID2A to regulate cell cycle kinetics in the developing vertebrate retina Prof Peter Hitchcock, Department of Ophthalmology and Visual Sciences, University of Michigan, Ann Arbor, Michigan, USA


Afternoon tea and poster viewing

 3:30pm-4:30pm SESSION 4: MK, stem cells and regeneration                                                                         

 Moderator: Mine Erguven, Ayan Bilir


Novel insights into the MK/PTN gene family revealed by deep (phospho) proteomic profiling of pluripotent and multipotent human stem cells Dr Laurence Brill, Director, Advanced Proteomics, Sanford-Burnham Medical Research Institute, La Jolla, California, USA

 4:00pm-4:30pm A role for midkine in early human development modelled by pluripotent stem cells Dr Ilyas Singec, Director, Cell Reprogramming, Sanford-Burnham Medical Research Institute, La Jolla, California, USA

Midkine and chondrocyte regeneration Prof Wei Han, School of Pharmacy Shanghai Jiao Tong University, Shanghai, China

 6:00pm - 8:00pm  Welcome reception, Istanbul University Rectorate gardens


Friday, 29th June 2012

 9:50am-11:00am SESSION 5: Second plenary                                    

 Moderator: Darren Jones

PLENARY 2: Midkine: at the intersection of neurobiology and cancer Prof Kenji Kadomatsu, Nagoya University Graduate School of Medicine, Nagoya, Japan


Morning tea and poster viewing

 11:30am-1:00pm SESSION 6: MK and Glioma                         

 Moderator: Kenji Kadomatsu
 11:30am-12:00pm Midkine as a factor for resistance to cannabinoid anti-cancer action in gliomas Dr Guillermo Velasco, Department of Biochemistry and Molecular Biology, School of Biology, Complutense University, Madrid, Spain
 12:00pm-12:30pm The effect of MK levels on hyperbaric oxygen therapy in a rat glioma model Dr Tolga Dündar, Faculty of Medicine Department of Neurosurgery, Bezmi Alem University, Istanbul, Turkey 



 2:00pm-2:30pm SESSION 7: MK in neurologic disorders                                   

 Moderator: Idit Shachar
 2:00pm-2:30pm Mice with genetic deletion of midkine exhibit early preclinical features of Parkinson’s disease Dr Rita Raisman-Vozari, Director of Research, Unité INSERM U679, Université Pierre et Marie Curie, Paris, France
 2:30pm-3:00pm Roles of midkine and pleiotrophin in drug addiction Behaviour and in drug-induced neurotoxicity and Parkinson's disease Prof Gonzalo Herradon, Laboratory of Pharmacology and Toxicology, Univ. San Pablo, Madrid, Spain


Afternoon tea and poster viewing

 3:30pm-4:30pm SESSION 8: MK - new horizons     

 Moderator: Takashi Muramatsu
 3:30pm-4:00pm Midkine deficiency increases the anabolic response of cortical bone to mechanical loading Dr Astrid Liedert, Institute of Orthopedic Research and Biomechanics, Center of Musculoskeletal Research, University of Ulm, Ulm, Germany
 4:00pm-4:30pm Local MK treatment improves wound healing in rats Assoc Prof Nuray Yazihan, Department of Physiology, Faculty of Medicine, Baskent University, Ankara, Turkey 

 4:30pm-5:00pm CLOSING DISCUSSION: The future and promise of MK

 PANEL: Takashi Muramatsu, Kenji Kadomatsu, Prof Peter Ferdinandy (PharmaHungary Group), Robert Clancy
 Moderator: Darren Jones

 General discussion for all participants:

  • The key scientific challenges remaining in MK biology
  • Emerging areas of interest
  • Therapeutic and diagnostic opportunities for MK

 7:00pm - 11:00pm  Conference dinner, Baltalimanı Bosphorus restaurant


Saturday, 30th June 2012

 10:00am - 2:00pm  Bosphorus Sightseeing Cruise, departs Barceló Saray Hotel