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2011
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Muramatsu, H., Yokoi, K., Chen, L., Ichihara-Tanaka, K., Kimura, T. & Muramatsu, T. Midkine as a factor to counteract the deposition of amyloid beta-peptide plaques: in vitro analysis and examination in knockout mice. Int Arch Med, 4, 1.
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2011
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Kato, K., Kosugi, T., Sato, W., Arata-Kawai, H., Ozaki, T., Tsuboi, N., Ito, I., Tawada, H., Yuzawa, Y., Matsuo, S., Kadomatsu, K. & Maruyama, S. Growth factor Midkine is involved in the pathogenesis of renal injury induced by protein overload containing endotoxin. Clinical and Experimental Nephrology, 1-9.
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2011
|
Liedert, A
Mattausch, L.,
Röntgen, V.,
Blakytny, R.,
Vogele, D.,
Pahl, M.,
Bindl, R.,
Neunaber, C., Catala-Lehnen, P., Beil, F. T., Marshall, R. P., Kanbach,
V., Baranowsky, A., Lehmann, W., Streichert, T., Ignatius, A.,
Muramastu, T., Schinke, T. & Amling, M. Increased trabecular bone
formation in mice lacking the growth factor midkine. J Bone Miner Res..
|
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2010
|
Sumida, A., Horiba, M., Ishiguro, H., Takenaka, H., Ueda, N., Ooboshi,
H., Opthof, T., Kadomatsu, K. & Kodama, I. Midkine gene transfer
after myocardial infarction in rats prevents remodelling and ameliorates
cardiac dysfunction. Cardiovasc Res, 86, 113-21.
|
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2010
|
Muramatsu, T. Midkine, a heparin-binding cytokine with multiple roles in development, repair and diseases. Proceedings of the Japan Academy, Series B, 86, 410-425.
|
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2010
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Matsui, T., Ichihara-Tanaka, K., Lan, C., Muramatsu, H., Kondou, T., Hirose, C., Sakuma, S. & Muramatsu, T. (2010) Midkine inhibitors: application of a simple assay procedure to screening of inhibitory compounds
International Archives of Medicine, 3.
|
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2010
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Lucas, S., Henze, G., Schnabel, D., Barthlen, W., Sakuma, S., Kurtz, A. & Driever, P. H. Serum levels of Midkine in children and adolescents without malignant disease. Pediatr Int, 52, 75-79.
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2009
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Hobo, A., Yuzawa, Y., Kosugi, T., Kato, N., Asai, N., Sato, W., Maruyama, S., Ito, Y., Kobori, H., Ikematsu, S., Nishiyama, A., Matsuo, S. & Kadomatsu, K. The growth factor midkine regulates the renin-angiotensin system in mice. J Clin Invest, 119, 1616-25.
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2009
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Ibusuki, M., Fujimori, H., Yamamoto, Y., Ota, K., Ueda, M., Shinriki, S., Taketomi, M., Sakuma, S., Shinohara, M., Iwase, H. & Ando, Y. Midkine in plasma as a novel breast cancer marker. Cancer Sci, 100, 1735-9.
|
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2009
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Lucas, S., Reindl, T., Henze, G., Kurtz, A., Sakuma, S. & Driever, P. H. Increased Midkine Serum Levels in Pediatric Embryonal Tumor Patients. J Pediatr Hematol Oncol.
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2009
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Ohgake, S., Shimizu, E., Hashimoto, K., Okamura, N., Koike, K., Koizumi, H., Fujisaki, M., Kanahara, N., Matsuda, S., Sutoh, C., Matsuzawa, D., Muramatsu, H., Muramatsu, T. & Iyo, M. Dopaminergic hypofunctions and prepulse inhibition deficits in mice lacking midkine. Prog Neuropsychopharmacol Biol Psychiatry, 33, 541-6.
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2009
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Sakakima, H., Yoshida, Y., Yamazaki, Y., Matsuda, F., Ikutomo, M., Ijiri, K., Muramatsu, H., Muramatsu, T. & Kadomatsu, K. Disruption of the midkine gene (Mdk) delays degeneration and regeneration in injured peripheral nerve. J Neurosci Res, 87, 2908-15.
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2009
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Takenaka, H., Horiba, M., Ishiguro, H., Sumida, A., Hojo, M., Usui, A., Akita, T., Sakuma, S., Ueda, Y., Kodama, I. & Kadomatsu, K. Midkine prevents ventricular remodeling and improves long-term survival after myocardial infarction. Am J Physiol Heart Circ Physiol, 296, H462-9.
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2008
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Fiegel, H. C., Kaifi, J. T., Wachowiak, R., Quaas, A., Aridome, K., Ichihara-Tanaka, K., Muramatsu, T., Metzger, R., Izbicki, J. R., Erttmann, R., Kluth, D. & Till, H. Midkine is highly expressed in neuroblastoma tissues. Pediatr Surg Int, 24, 1355-9.
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2008
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Ikematsu, S., Nakagawara, A., Nakamura, Y., Ohira, M., Shinjo, M., Kishida, S. & Kadomatsu, K. Plasma midkine level is a prognostic factor for human neuroblastoma. Cancer Sci, 99, 2070-4.
|
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2008
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Kadomatsu, K. The Midkine Family and Its Receptors. Experimental Glycoscience. Springer.
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2008
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Muramatsu, T. & Muramatsu, H. Glycosaminoglycan-binding cytokines as tumor markers. Proteomics, 8, 3350-9
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2008
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Narita, H., Chen, S., Komori, K. & Kadomatsu, K. Midkine is expressed by infiltrating macrophages in in-stent restenosis in hypercholesterolemic rabbits. J Vasc Surg, 47, 1322-9.
|
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2008
|
Tanabe, K., Matsumoto, M., Ikematsu, S., Nagase, S., Hatakeyama, A., Takano, T., Niikura, H., Ito, K., Kadomatsu, K., Hayashi, S. & Yaegashi, N. Midkine and its clinical significance in endometrial carcinoma. Cancer Sci, 99, 1125-30.
|
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2008
|
Wang, J., Takeuchi, H., Sonobe, Y., Jin, S., Mizuno, T., Miyakawa, S., Fujiwara, M., Nakamura, Y., Kato, T., Muramatsu, H., Muramatsu, T. & Suzumura, A. Inhibition of midkine alleviates experimental autoimmune encephalomyelitis through the expansion of regulatory T cell population. Proc Natl Acad Sci U S A, 105, 3915-20.
|
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2008
|
Yoshida, Y., Ikematsu, S., Muramatsu, H., Sakakima, H., Mizuma, N., Matsuda, F., Sonoda, K., Umehara, F., Ohkubo, R., Matsuura, E., Goto, M., Osame, M. & Muramatsu, T. Expression of the heparin-binding growth factor midkine in the cerebrospinal fluid of patients with neurological disorders. Intern Med, 47, 83-9.
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2007
|
Chen, S., Bu, G., Takei, Y., Sakamoto, K., Ikematsu, S., Muramatsu, T. & Kadomatsu, K. Midkine and LDL-receptor-related protein 1 contribute to the anchorage-independent cell growth of cancer cells. J Cell Sci, 120, 4009-15.
|
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2007
|
Hidaka, H., Yagasaki, H., Takahashi, Y., Hama, A., Nishio, N., Tanaka, M., Yoshida, N., Villalobos, I. B., Wang, Y., Xu, Y., Horibe, K., Chen, S., Kadomatsu, K. & Kojima, S. Increased midkine gene expression in childhood B-precursor acute lymphoblastic leukemia. Leuk Res, 31, 1045-51.
|
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2007
|
Hirota, Y., Osuga, Y., Nose, E., Koga, K., Yoshino, O., Hirata, T., Yano, T., Tsutsumi, O., Sakuma, S., Muramatsu, T. & Taketani, Y. The presence of midkine and its possible implication in human ovarian follicles. Am J Reprod Immunol, 58, 367-73.
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2007
|
Ishiguro, H., Takenaka, H., Sumida, A., Kadomatsu, K., Murohara, T., Kodama, I. & Horiba, M. Abstract 1062: A Single Intracoronary Injection of Midkine Reduces Ischemia/reperfusion Injury in Swine Hearts: A Novel Therapeutic Approach for Acute Coronary Syndrome. Circulation, 116, II_212.
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2007
|
Kaifi, J. T., Fiegel, H. C., Rafnsdottir, S. L., Aridome, K., Schurr, P. G., Reichelt, U., Wachowiak, R., Kleinhans, H., Yekebas, E. F., Mann, O., Ichihara-Tanaka, K., Muramatsu, T., Kluth, D., Strate, T. & Izbicki, J. R. Midkine as a prognostic marker for gastrointestinal stromal tumors. J Cancer Res Clin Oncol, 133, 431-5.
|
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2007
|
Kosugi, T., Yuzawa, Y., Sato, W., Arata-Kawai, H., Suzuki, N., Kato, N., Matsuo, S. & Kadomatsu, K. Midkine is involved in tubulointerstitial inflammation associated with diabetic nephropathy. Lab Invest, 87, 903-13.
|
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2007
|
Maehara, H., Kaname, T., Yanagi, K., Hanzawa, H., Owan, I., Kinjou, T., Kadomatsu, K., Ikematsu, S., Iwamasa, T., Kanaya, F. & Naritomi, K. Midkine as a novel target for antibody therapy in osteosarcoma. Biochem Biophys Res Commun, 358, 757-62.
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2006
|
Banno, H., Takei, Y., Muramatsu, T., Komori, K. & Kadomatsu, K. Controlled release of small interfering RNA targeting midkine attenuates intimal hyperplasia in vein grafts. J Vasc Surg, 44, 633-41.
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2006
|
Fukada, M., Fujikawa, A., Chow, J. P., Ikematsu, S., Sakuma, S. & Noda, M. Protein tyrosine phosphatase receptor type Z is inactivated by ligand-induced oligomerization. FEBS Lett, 580, 4051-6.
|
|
2006
|
Horiba, M., Kadomatsu, K., Yasui, K., Lee, J. K., Takenaka, H., Sumida, A., Kamiya, K., Chen, S., Sakuma, S., Muramatsu, T. & Kodama, I. Midkine plays a protective role against cardiac ischemia/reperfusion injury through a reduction of apoptotic reaction. Circulation, 114, 1713-20.
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2006
|
Ichihara-Tanaka, K., Oohira, A., Rumsby, M. & Muramatsu, T. Neuroglycan C is a novel midkine receptor involved in process elongation of oligodendroglial precursor-like cells. J Biol Chem, 281, 30857-64.
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2006
|
Inoh, K., Muramatsu, H., Torii, S., Ikematsu, S., Oda, M., Kumai, H., Sakuma, S., Inui, T., Kimura, T. & Muramatsu, T. Doxorubicin-conjugated anti-midkine monoclonal antibody as a potential anti-tumor drug. Jpn J Clin Oncol, 36, 207-11.
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2006
|
Kosugi, T., Yuzawa, Y., Sato, W., Kawai, H., Matsuo, S., Takei, Y., Muramatsu, T. & Kadomatsu, K. Growth factor midkine is involved in the pathogenesis of diabetic nephropathy. Am J Pathol, 168, 9-19.
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2006a
|
Muramatsu, T., Muramatsu, H. & Kojima, T. Identification of proteoglycan-binding proteins. Methods Enzymol, 416, 263-78.
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2006b
|
Nakagawa, T., Kubota, T., Ido, K., Sakuma, T. & Matsuda, K. Gene expression profiles of 1-(4-amino-2-methyl-5-pyrimidinyl)-methyl-3-(2-chloroethyl)-3-nitrosourea (ACNU)-resistant C6 rat glioma cells. J Neurooncol, 79, 271-9.
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2006
|
Salama, R. H., Muramatsu, H., Zou, P., Okayama, M. & Muramatsu, T. Midkine, a heparin-binding growth factor, produced by the host enhances metastasis of Lewis lung carcinoma cells. Cancer Lett, 233, 16-20.
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2006
|
Takei, Y., Kadomatsu, K., Goto, T. & Muramatsu, T. Combinational antitumor effect of siRNA against midkine and paclitaxel on growth of human prostate cancer xenografts. Cancer, 107, 864-73.
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2006
|
Yamamoto, H., Muramatsu, H., Nakanishi, T., Natori, Y., Sakuma, S., Ishiguro, N. & Muramatsu, T. Midkine as a molecular target: comparison of effects of chondroitin sulfate E and siRNA. Biochem Biophys Res Commun, 351, 915-9.
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2006a
|
Zou, P., Muramatsu, H., Sone, M., Hayashi, H., Nakashima, T. & Muramatsu, T. Mice doubly deficient in the midkine and pleiotrophin genes exhibit deficits in the expression of beta-tectorin gene and in auditory response. Lab Invest, 86, 645-53.
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2006b
|
Zou, P., Muramatsu, H., Miyata, T. & Muramatsu, T. Midkine, a heparin-binding growth factor, is expressed in neural precursor cells and promotes their growth. J Neurochem, 99, 1470-9.
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2005
|
Friedrich, C., Holtkamp, N., Cinatl, J., Jr., Sakuma, S., Mautner, V. F., Wellman, S., Michaelis, M., Henze, G., Kurtz, A. & Driever, P. H. Overexpression of Midkine in malignant peripheral nerve sheath tumor cells inhibits apoptosis and increases angiogenic potency. Int J Oncol, 27, 1433-40.
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2005
|
Hayashi, K., Banno, H., Kadomatsu, K., Takei, Y., Komori, K. & Muramatsu, T. Antisense oligodeoxyribonucleotide as to the growth factor midkine suppresses neointima formation induced by balloon injury. Am J Physiol Heart Circ Physiol, 288, H2203-9.
|
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2005
|
Hirota, Y., Osuga, Y., Koga, K., Yoshino, O., Hirata, T., Harada, M., Morimoto, C., Yano, T., Tsutsumi, O., Sakuma, S., Muramatsu, T. & Taketani, Y. Possible implication of midkine in the development of endometriosis. Hum Reprod, 20, 1084-9.
|
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2005
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Kadomatsu, K. The midkine family in cancer, inflammation and neural development. Nagoya J Med Sci, 67, 71-82
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2005
|
Obata, Y., Kikuchi, S., Lin, Y., Yagyu, K., Muramatsu, T. & Kumai, H. Serum midkine concentrations and gastric cancer. Cancer Sci, 96, 54-6.
|
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2005
|
Salama, R. H., Muramatsu, H., Shimizu, E., Hashimoto, K., Ohgake, S., Watanabe, H., Komatsu, N., Okamura, N., Koike, K., Shinoda, N., Okada, S., Iyo, M. & Muramatsu, T. Increased midkine levels in sera from patients with Alzheimer's disease. Prog Neuropsychopharmacol Biol Psychiatry, 29, 611-6.
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2005
|
Sato, W., Takei, Y., Yuzawa, Y., Matsuo, S., Kadomatsu, K. & Muramatsu, T. Midkine antisense oligodeoxyribonucleotide inhibits renal damage induced by ischemic reperfusion. Kidney Int, 67, 1330-9.
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2005
|
Takada, J., Ooboshi, H., Ago, T., Kitazono, T., Yao, H., Kadomatsu, K., Muramatsu, T., Ibayashi, S. & Iida, M. Postischemic gene transfer of midkine, a neurotrophic factor, protects against focal brain ischemia. Gene Ther, 12, 487-93.
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2005
|
Takei, Y., Kadomatsu, K., Yuasa, K., Sato, W. & Muramatsu, T. Morpholino antisense oligomer targeting human midkine: its application for cancer therapy. Int J Cancer, 114, 490-7.
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2005
|
Vanucci, S., Minerdi, D., Kadomatsu, K., Mengoni, A. & Bazzicalupo, M. Putative midkine family protein up-regulation in Patella caerulea (Mollusca, Gastropoda) exposed to sublethal concentrations of cadmium. Aquat Toxicol, 75, 374-9.
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2004
|
Inoh, K., Muramatsu, H., Ochiai, K., Torii, S. & Muramatsu, T. Midkine, a heparin-binding cytokine, plays key roles in intraperitoneal adhesions. Biochem Biophys Res Commun, 317, 108-13.
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2004
|
Kadomatsu, K. & Muramatsu, T. Midkine and pleiotrophin in neural development and cancer. Cancer Lett, 204, 127-43.
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2004
|
Kawai, H., Sato, W., Yuzawa, Y., Kosugi, T., Matsuo, S., Takei, Y., Kadomatsu, K. & Muramatsu, T. Lack of the growth factor midkine enhances survival against cisplatin-induced renal damage. Am J Pathol, 165, 1603-12.
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2004
|
Maruyama, K., Muramatsu, H., Ishiguro, N. & Muramatsu, T. Midkine, a heparin-binding growth factor, is fundamentally involved in the pathogenesis of rheumatoid arthritis. Arthritis Rheum, 50, 1420-9.
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2004
|
Mashour, G. A., Driever, P. H., Hartmann, M., Drissel, S. N., Zhang, T., Scharf, B., Felderhoff-Muser, U., Sakuma, S., Friedrich, R. E., Martuza, R. L., Mautner, V. F. & Kurtz, A. Circulating growth factor levels are associated with tumorigenesis in neurofibromatosis type 1. Clin Cancer Res, 10, 5677-83.
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2004
|
Muramatsu, H., Zou, P., Suzuki, H., Oda, Y., Chen, G. Y., Sakaguchi, N., Sakuma, S., Maeda, N., Noda, M., Takada, Y. & Muramatsu, T. alpha4beta1- and alpha6beta1-integrins are functional receptors for midkine, a heparin-binding growth factor. J Cell Sci, 117, 5405-15.
|
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2004
|
Ochiai, K., Muramatsu, H., Yamamoto, S., Ando, H. & Muramatsu, T. The role of midkine and pleiotrophin in liver regeneration. Liver Int, 24, 484-91.
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2004
|
Ohuchida, T., Okamoto, K., Akahane, K., Higure, A., Todoroki, H., Abe, Y., Kikuchi, M., Ikematsu, S., Muramatsu, T. & Itoh, H. Midkine protects hepatocellular carcinoma cells against TRAIL-mediated apoptosis through down-regulation of caspase-3 activity. Cancer, 100, 2430-6.
|
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2004a
|
Sakakima, H., Yoshida, Y., Kadomatsu, K., Yuzawa, Y., Matsuo, S. & Muramatsu, T. Midkine expression in rat spinal motor neurons following sciatic nerve injury. Brain Res Dev Brain Res, 153, 251-60.
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2004b
|
Sakakima, H., Yoshida, Y., Muramatsu, T., Yone, K., Goto, M., Ijiri, K. & Izumo, S. Traumatic injury-induced midkine expression in the adult rat spinal cord during the early stage. J Neurotrauma, 21, 471-7.
|
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2004
|
Suzuki, N., Shibata, Y., Urano, T., Murohara, T., Muramatsu, T. & Kadomatsu, K. Proteasomal degradation of the nuclear targeting growth factor midkine. J Biol Chem, 279, 17785-91.
|
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2004a
|
Yu, L., Hamada, K., Namba, M., Kadomatsu, K., Muramatsu, T., Matsubara, S. & Tagawa, M. Insertion of an exogenous promoter in the E1A regulatory region of adenovirus does not disturb viral replication despite reduced E1A transcription. Cancer Lett, 203, 51-7.
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2004b
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Yu, L., Hamada, K., Namba, M., Kadomatsu, K., Muramatsu, T., Matsubara, S. & Tagawa, M. Midkine promoter-driven suicide gene expression and -mediated adenovirus replication produced cytotoxic effects to immortalised and tumour cells. Eur J Cancer, 40, 1787-94.
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2004c
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Yu, L., Yamamoto, N., Kadomatsu, K., Muramatsu, T., Matsubara, S., Sakiyama, S. & Tagawa, M. Midkine promoter can mediate transcriptional activation of a fused suicide gene in a broader range of human breast cancer compared with c-erbB-2 promoter. Oncology, 66, 143-9.
|
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2003a
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Ikematsu, S., Nakagawara, A., Nakamura, Y., Sakuma, S., Wakai, K., Muramatsu, T. & Kadomatsu, K. Correlation of elevated level of blood midkine with poor prognostic factors of human neuroblastomas. Br J Cancer, 88, 1522-6.
|
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2003b
|
Ikematsu, S., Okamoto, K., Yoshida, Y., Oda, M., Sugano-Nagano, H., Ashida, K., Kumai, H., Kadomatsu, K., Muramatsu, H., Takashi, M. & Sakuma, S. High levels of urinary midkine in various cancer patients. Biochem Biophys Res Commun, 306, 329-32.
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2003
|
Sakaguchi, N., Muramatsu, H., Ichihara-Tanaka, K., Maeda, N., Noda, M., Yamamoto, T., Michikawa, M., Ikematsu, S., Sakuma, S. & Muramatsu, T. Receptor-type protein tyrosine phosphatase zeta as a component of the signaling receptor complex for midkine-dependent survival of embryonic neurons. Neurosci Res, 45, 219-24.
|
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2003
|
Sakiyama, S., Yu, L., Tomizawa, M., Shimada, H., Kadomatsu, K., Muramatsu, T., Ikematsu, S., Nakagawara, A. & Tagawa, M. Utilization of the promoter region of the midkine gene as a tool to drive therapeutic genes in a tumor specific manner. Adv Enzyme Regul, 43, 57-66.
|
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2003a
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Shimada, H., Nabeya, Y., Okazumi, S., Matsubara, H., Kadomatsu, K., Muramatsu, T., Ikematsu, S., Sakuma, S. & Ochiai, T. Increased serum midkine concentration as a possible tumor marker in patients with superficial esophageal cancer. Oncol Rep, 10, 411-4.
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2003b
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Shimada, H., Nabeya, Y., Tagawa, M., Okazumi, S., Matsubara, H., Kadomatsu, K., Muramatsu, T., Ikematsu, S., Sakuma, S. & Ochiai, T. Preoperative serum midkine concentration is a prognostic marker for esophageal squamous cell carcinoma. Cancer Sci, 94, 628-32.
|
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2003
|
Shimizu, E., Hashimoto, K., Salama, R. H., Watanabe, H., Komatsu, N., Okamura, N., Koike, K., Shinoda, N., Nakazato, M., Kumakiri, C., Okada, S., Muramatsu, H., Muramatsu, T. & Iyo, M. Two clusters of serum midkine levels in drug-naive patients with schizophrenia. Neurosci Lett, 344, 95-8.
|
|
2003
|
Tomizawa, M., Yu, L., Wada, A., Tamaoki, T., Kadomatsu, K., Muramatsu, T., Matsubara, S., Watanabe, K., Ebara, M., Saisho, H., Sakiyama, S. & Tagawa, M. A promoter region of the midkine gene that is frequently expressed in human hepatocellular carcinoma can activate a suicide gene as effectively as the alpha-fetoprotein promoter. Br J Cancer, 89, 1086-90.
|
|
2003
|
Yu, L., Ugai, S., J, O. W., Namba, M., Kadomatsu, K., Muramatsu, T., Matsubara, S., Sakiyama, S. & Tagawa, M. Cell growth- and P53-dependent transcriptional activity of the midkine promoter confers suicide gene expression in tumor cells. Oncol Rep, 10, 1301-5.
|
|
2003
|
Zou, P., Zou, K., Muramatsu, H., Ichihara-Tanaka, K., Habuchi, O., Ohtake, S., Ikematsu, S., Sakuma, S. & Muramatsu, T. Glycosaminoglycan structures required for strong binding to midkine, a heparin-binding growth factor. Glycobiology, 13, 35-42.
|
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2002
|
Adachi, Y., Matsubara, S., Muramatsu, T., Curiel, D. T. & Reynolds, P. N. Midkine promoter-based adenoviral suicide gene therapy to midkine-positive pediatric tumor. J Pediatr Surg, 37, 588-92.
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2002
|
Matsuura, O., Kadomatsu, K., Takei, Y., Uchimura, K., Mimura, S., Watanabe, K. & Muramatsu, T. Midkine expression is associated with postnatal development of the lungs. Cell Struct Funct, 27, 109-15.
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2002
|
Muramatsu, T. Midkine and pleiotrophin: two related proteins involved in development, survival, inflammation and tumorigenesis. J Biochem, 132, 359-71.
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2002
|
Sato, W., Yuzawa, Y., Kadomatsu, K., Tayasu, T., Muramatsu, H., Muramatsu, T. & Matsuo, S. Midkine expression in the course of nephrogenesis and its role in ischaemic reperfusion injury. Nephrol Dial Transplant, 17 Suppl 9, 52-4.
|
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2002
|
Shibata, Y., Muramatsu, T., Hirai, M., Inui, T., Kimura, T., Saito, H., Mccormick, L. M., Bu, G. & Kadomatsu, K. Nuclear targeting by the growth factor midkine. Mol Cell Biol, 22, 6788-96.
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2002
|
Sumi, Y., Muramatsu, H., Takei, Y., Hata, K., Ueda, M. & Muramatsu, T. Midkine, a heparin-binding growth factor, promotes growth and glycosaminoglycan synthesis of endothelial cells through its action on smooth muscle cells in an artificial blood vessel model. J Cell Sci, 115, 2659-67.
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2002
|
Takei, Y., Kadomatsu, K., Itoh, H., Sato, W., Nakazawa, K., Kubota, S. & Muramatsu, T. 5'-,3'-inverted thymidine-modified antisense oligodeoxynucleotide targeting midkine. Its design and application for cancer therapy. J Biol Chem, 277, 23800-6.
|
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2002
|
Yoshida, Y., Tomizawa, M., Bahar, R., Miyauchi, M., Yamaguchi, T., Saisho, H., Kadomatsu, K., Muramatsu, T., Matsubara, S., Sakiyama, S. & Tagawa, M. A promoter region of midkine gene can activate transcription of an exogenous suicide gene in human pancreatic cancer. Anticancer Res, 22, 117-20.
|
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2001
|
Adachi, Y., Reynolds, P. N., Yamamoto, M., Wang, M., Takayama, K., Matsubara, S., Muramatsu, T. & Curiel, D. T. A midkine promoter-based conditionally replicative adenovirus for treatment of pediatric solid tumors and bone marrow tumor purging. Cancer Res, 61, 7882-8.
|
|
2001
|
Hayashi, K., Kadomatsu, K. & Muramatsu, T. Requirement of chondroitin sulfate/dermatan sulfate recognition in midkine-dependent migration of macrophages. Glycoconj J, 18, 401-6.
|
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2001
|
Jia, X. Q., Nakashima, T., Kadomatsu, K. & Muramatsu, T. Expression of midkine in the cochlea. Hear Res, 160, 10-4.
|
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2001
|
Kurosawa, N., Chen, G. Y., Kadomatsu, K., Ikematsu, S., Sakuma, S. & Muramatsu, T. Glypican-2 binds to midkine: the role of glypican-2 in neuronal cell adhesion and neurite outgrowth. Glycoconj J, 18, 499-507.
|
|
2001
|
Miyauchi, M., Yoshida, Y., Tada, Y., Narita, M., Maeda, T., Bahar, R., Kadomatsu, K., Muramatsu, T., Matsubara, S., Nakagawara, A., Sakiyama, S. & Tagawa, M. Expression of herpes simplex virus-thymidine kinase gene controlled by a promoter region of the midkine gene confers selective cytotoxicity to ganciclovir in human carcinoma cells. Int J Cancer, 91, 723-7.
|
|
2001
|
Qi, M., Ikematsu, S., Maeda, N., Ichihara-Tanaka, K., Sakuma, S., Noda, M., Muramatsu, T. & Kadomatsu, K. Haptotactic migration induced by midkine. Involvement of protein-tyrosine phosphatase zeta. Mitogen-activated protein kinase, and phosphatidylinositol 3-kinase. J Biol Chem, 276, 15868-75.
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2001
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Salama, R. H., Muramatsu, H., Zou, K., Inui, T., Kimura, T. & Muramatsu, T. Midkine binds to 37-kDa laminin binding protein precursor, leading to nuclear transport of the complex. Exp Cell Res, 270, 13-20.
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2001
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Sato, W., Kadomatsu, K., Yuzawa, Y., Muramatsu, H., Hotta, N., Matsuo, S. & Muramatsu, T. Midkine is involved in neutrophil infiltration into the tubulointerstitium in ischemic renal injury. J Immunol, 167, 3463-9.
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2001
|
Takahashi, A., Muramatsu, H., Takagi, S., Fujisawa, H., Miyake, Y. & Muramatsu, T. A splicing factor, Prp8: preferential localization in the testis and ovary in adult mice. J Biochem, 129, 599-606.
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2001
|
Takei, Y., Kadomatsu, K., Matsuo, S., Itoh, H., Nakazawa, K., Kubota, S. & Muramatsu, T. Antisense oligodeoxynucleotide targeted to Midkine, a heparin-binding growth factor, suppresses tumorigenicity of mouse rectal carcinoma cells. Cancer Res, 61, 8486-91.
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2001
|
Yoshida, Y., Ikematsu, S., Moritoyo, T., Goto, M., Tsutsui, J., Sakuma, S., Osame, M. & Muramatsu, T. Intraventricular administration of the neurotrophic factor midkine ameliorates hippocampal delayed neuronal death following transient forebrain ischemia in gerbils. Brain Res, 894, 46-55.
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2000
|
Adachi, Y., Reynolds, P. N., Yamamoto, M., Grizzle, W. E., Overturf, K., Matsubara, S., Muramatsu, T. & Curiel, D. T. Midkine promoter-based adenoviral vector gene delivery for pediatric solid tumors. Cancer Res, 60, 4305-10.
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2000
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Fan, Q. W., Muramatsu, T. & Kadomatsu, K. Distinct expression of midkine and pleiotrophin in the spinal cord and placental tissues during early mouse development. Dev Growth Differ, 42, 113-9.
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2000
|
Horiba, M., Kadomatsu, K., Nakamura, E., Muramatsu, H., Ikematsu, S., Sakuma, S., Hayashi, K., Yuzawa, Y., Matsuo, S., Kuzuya, M., Kaname, T., Hirai, M., Saito, H. & Muramatsu, T. Neointima formation in a restenosis model is suppressed in midkine-deficient mice. J Clin Invest, 105, 489-95.
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2000a
|
Ikeda, S., Nishikimi, A., Ichihara-Tanaka, K., Muramatsu, T. & Yamada, M. cDNA cloning of bovine midkine and production of the recombinant protein, which affects in vitro maturation of bovine oocytes. Mol Reprod Dev, 57, 99-107.
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2000b
|
Ikeda, S., Ichihara-Tanaka, K., Azuma, T., Muramatsu, T. & Yamada, M. Effects of midkine during in vitro maturation of bovine oocytes on subsequent developmental competence. Biol Reprod, 63, 1067-74.
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2000
|
Ikematsu, S., Yano, A., Aridome, K., Kikuchi, M., Kumai, H., Nagano, H., Okamoto, K., Oda, M., Sakuma, S., Aikou, T., Muramatsu, H., Kadomatsu, K. & Muramatsu, T. Serum midkine levels are increased in patients with various types of carcinomas. Br J Cancer, 83, 701-6.
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2000
|
Inui, T., Nakao, M., Nishio, H., Nishiuchi, Y., Kojima, S., Muramatsu, T. & Kimura, T. Solution synthesis and biological activity of human pleiotrophin, a novel heparin-binding neurotrophic factor consisting of 136 amino acid residues with five disulfide bonds. J Pept Res, 55, 384-97.
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2000
|
Kadomatsu, K. [Recent progress of midkine research on cancer]. Nippon Rinsho, 58, 1337-47.
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2000
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Kato, H., Watanabe, K., Murari, M., Isogai, C., Kinoshita, T., Nagai, H., Ohashi, H., Nagasaka, T., Kadomatsu, K., Muramatsu, H., Muramatsu, T., Saito, H., Mori, N. & Murate, T. Midkine expression in Reed-Sternberg cells of Hodgkin's disease. Leuk Lymphoma, 37, 415-24.
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2000
|
Kurosawa, N., Kadomatsu, K., Ikematsu, S., Sakuma, S., Kimura, T. & Muramatsu, T. Midkine binds specifically to sulfatide the role of sulfatide in cell attachment to midkine-coated surfaces. Eur J Biochem, 267, 344-51.
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2000a
|
Muramatsu, H., Zou, K., Sakaguchi, N., Ikematsu, S., Sakuma, S. & Muramatsu, T. LDL receptor-related protein as a component of the midkine receptor. Biochem Biophys Res Commun, 270, 936-41.
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2000
|
Muramatsu, T. Protein-bound carbohydrates on cell-surface as targets of recognition: an odyssey in understanding them. Glycoconj J, 17, 577-95.
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2000
|
Narita, M., Takanaga, K., Yoshida, Y., Kadomatsu, K., Muramatsu, T., Matsubara, S., Hamada, H., Goto, S., Saisho, H., Sakiyama, S. & Tagawa, M. Polyadenylation signal facilitates the expression of foreign gene that is driven by an internal promoter located in the reverse orientation to long terminal repeat of retrovirus. Anticancer Res, 20, 279-82.
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2000
|
Qi, M., Ikematsu, S., Ichihara-Tanaka, K., Sakuma, S., Muramatsu, T. & Kadomatsu, K. Midkine rescues Wilms' tumor cells from cisplatin-induced apoptosis: regulation of Bcl-2 expression by Midkine. J Biochem, 127, 269-77.
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2000
|
Sumi, Y., Muramatsu, H., Hata, K., Ueda, M. & Muramatsu, T. Midkine enhances early stages of collagen gel contraction. J Biochem, 127, 247-51.
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2000
|
Tran, Q. K., Watanabe, H., Le, H. Y., Yang, J., Takeuchi, K., Kadomatsu, K., Muramatsu, T. & Ohashi, K. Midkine inhibits bradykinin-stimulated Ca(2+) signaling and nitric oxide production in endothelial cells. Biochem Biophys Res Commun, 276, 830-6.
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2000
|
Tsutsumi, M., Kadomatsu, K., Tsujiuchi, T., Sakitani, H., Ikematsu, S., Kubozoe, T., Yoshimoto, M., Muramatsu, T., Sakuma, S. & Konishi, Y. Overexpression of midkine in pancreatic duct adenocarcinomas induced by N-Nitrosobis(2-oxopropyl)amine in hamsters and their cell lines. Jpn J Cancer Res, 91, 979-86.
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|
2000
|
Ueoka, C., Kaneda, N., Okazaki, I., Nadanaka, S., Muramatsu, T. & Sugahara, K. Neuronal cell adhesion, mediated by the heparin-binding neuroregulatory factor midkine, is specifically inhibited by chondroitin sulfate E. Structural ans functional implications of the over-sulfated chondroitin sulfate. J Biol Chem, 275, 37407-13
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2000
|
Zou, K., Muramatsu, H., Ikematsu, S., Sakuma, S., Salama, R. H., Shinomura, T., Kimata, K. & Muramatsu, T. A heparin-binding growth factor, midkine, binds to a chondroitin sulfate proteoglycan, PG-M/versican. Eur J Biochem, 267, 4046-53.
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1999
|
Iwashita, N., Muramatsu, H., Toriyama, K., Torii, S. & Muramatsu, T. Expression of midkine in normal and burn sites of rat skin. Burns, 25, 119-24.
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1999
|
Koide, N., Hada, H., Shinji, T., Ujike, K., Hirasaki, S., Yumoto, Y., Hanafusa, T., Kadomatsu, K., Muramatsu, H., Muramatsu, T. & Tsuji, T. Expression of the midkine gene in human hepatocellular carcinomas. Hepatogastroenterology, 46, 3189-96.
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1999
|
Konishi, N., Nakamura, M., Nakaoka, S., Hiasa, Y., Cho, M., Uemura, H., Hirao, Y., Muramatsu, T. & Kadomatsu, K. Immunohistochemical analysis of midkine expression in human prostate carcinoma. Oncology, 57, 253-7.
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1999
|
Maeda, N., Ichihara-Tanaka, K., Kimura, T., Kadomatsu, K., Muramatsu, T. & Noda, M. A receptor-like protein-tyrosine phosphatase PTPzeta/RPTPbeta binds a heparin-binding growth factor midkine. Involvement of arginine 78 of midkine in the high affinity binding to PTPzeta. J Biol Chem, 274, 12474-9.
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1999
|
Matsuzawa, M., Muramatsu, T., Yamamori, T., Knoll, W. & Yano, R. Novel neuronal effects of midkine on embryonic cerebellar neurons examined using a defined culture system. Cell Mol Neurobiol, 19, 209-21.
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1999
|
Miyauchi, M., Shimada, H., Kadomatsu, K., Muramatsu, T., Matsubara, S., Ikematsu, S., Takenaga, K., Asano, T., Ochiai, T., Sakiyama, S. & Tagawa, M. Frequent expression of midkine gene in esophageal cancer suggests a potential usage of its promoter for suicide gene therapy. Jpn J Cancer Res, 90, 469-75.
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1999
|
Ohta, S., Muramatsu, H., Senda, T., Zou, K., Iwata, H. & Muramatsu, T. Midkine is expressed during repair of bone fracture and promotes chondrogenesis. J Bone Miner Res, 14, 1132-44.
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1999a
|
Owada, K., Sanjyo, N., Kobayashi, T., Kamata, T., Mizusawa, H., Muramatsu, H., Muramatsu, T. & Michikawa, M. Midkine inhibits apoptosis via extracellular signal regulated kinase (ERK) activation in PC12 cells. J Med Dent Sci, 46, 45-51.
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1999b
|
Owada, K., Sanjo, N., Kobayashi, T., Mizusawa, H., Muramatsu, H., Muramatsu, T. & Michikawa, M. Midkine inhibits caspase-dependent apoptosis via the activation of mitogen-activated protein kinase and phosphatidylinositol 3-kinase in cultured neurons. J Neurochem, 73, 2084-92.
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1999
|
Sakitani, H., Tsutsumi, M., Kadomatsu, K., Ikematsu, S., Takahama, M., Iki, K., Tsujiuchi, T., Muramatsu, T., Sakuma, S., Sakaki, T. & Konishi, Y. Overexpression of midkine in lung tumors induced by N-nitrosobis(2-hydroxypropyl)amine in rats and its increase with progression. Carcinogenesis, 20, 465-9.
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|
1999
|
Yamakawa, T., Kurosawa, N., Kadomatsu, K., Matsui, T., Itoh, K., Maeda, N., Noda, M. & Muramatsu, T. Levels of expression of pleiotrophin and protein tyrosine phosphatase zeta are decreased in human colorectal cancers. Cancer Lett, 135, 91-6.
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|
1999
|
Ye, C., Qi, M., Fan, Q. W., Ito, K., Akiyama, S., Kasai, Y., Matsuyama, M., Muramatsu, T. & Kadomatsu, K. Expression of midkine in the early stage of carcinogenesis in human colorectal cancer. Br J Cancer, 79, 179-84.
|
|
1998
|
Aridome, K., Takao, S., Kaname, T., Kadomatsu, K., Natsugoe, S., Kijima, F., Aikou, T. & Muramatsu, T. Truncated midkine as a marker of diagnosis and detection of nodal metastases in gastrointestinal carcinomas. Br J Cancer, 78, 472-7.
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|
1998a
|
Fan, Q. W., Kadomatsu, K., Uchimura, K. & Muramatsu, T. Embigin/basigin subgroup of the immunoglobulin superfamily: different modes of expression during mouse embryogenesis and correlated expression with carbohydrate antigenic markers. Dev Growth Differ, 40, 277-86.
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1998b
|
Fan, Q. W., Yuasa, S., Kuno, N., Senda, T., Kobayashi, M., Muramatsu, T. & Kadomatsu, K. Expression of basigin, a member of the immunoglobulin superfamily, in the mouse central nervous system. Neurosci Res, 30, 53-63.
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1998
|
Fujisawa, K., Matsumoto, Y., Muramatsu, H., Shinzato, T., Hiramatsu, K., Horie, K., Cai, Z., Oka, H., Amano, I., Muramatsu, T. & Maeda, K. Increased serum midkine levels during hemodialysis using heparin in chronic renal failure. J Biochem, 123, 864-9.
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|
1998
|
Igakura, T., Kadomatsu, K., Kaname, T., Muramatsu, H., Fan, Q. W., Miyauchi, T., Toyama, Y., Kuno, N., Yuasa, S., Takahashi, M., Senda, T., Taguchi, O., Yamamura, K., Arimura, K. & Muramatsu, T. A null mutation in basigin, an immunoglobulin superfamily member, indicates its important roles in peri-implantation development and spermatogenesis. Dev Biol, 194, 152-65.
|
|
1998a
|
Kadomatsu, K. cDNA Cloning and Sequencing of a New Gene Intensely Expressed in Early Differentiation Stages of Embryonal Carcinoma Cells and In Mid-Gestation Period of Mouse Embryogenesis. Biochem Biophys Res Commun, 151, 1312-1318.
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|
1998b
|
Kadomatsu, K. [Midkine, a heparin-binding growth factor: its discovery and functions]. Seikagaku, 70, 1315-25.
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|
1998
|
Kuno, N., Kadomatsu, K., Fan, Q. W., Hagihara, M., Senda, T., Mizutani, S. & Muramatsu, T. Female sterility in mice lacking the basigin gene, which encodes a transmembrane glycoprotein belonging to the immunoglobulin superfamily. FEBS Lett, 425, 191-4.
|
|
1998
|
Maekawa, M., Suzuki-Toyota, F., Toyama, Y., Kadomatsu, K., Hagihara, M., Kuno, N., Muramatsu, T., Dohmae, K. & Yuasa, S. Stage-specific localization of basigin, a member of the immunoglobulin superfamily, during mouse spermatogenesis. Arch Histol Cytol, 61, 405-15.
|
|
1998
|
Miyashiro, M., Kadomatsu, K., Ogata, N., Yamamoto, C., Takahashi, K., Uyama, M., Muramatsu, H. & Muramatsu, T. Midkine expression in transient retinal ischemia in the rat. Curr Eye Res, 17, 9-13.
|
|
1998
|
Mizuki, K., Kadomatsu, K., Hata, K., Ito, T., Fan, Q. W., Kage, Y., Fukumaki, Y., Sakaki, Y., Takeshige, K. & Sumimoto, H. Functional modules and expression of mouse p40(phox) and p67(phox), SH3-domain-containing proteins involved in the phagocyte NADPH oxidase complex. Eur J Biochem, 251, 573-82.
|
|
1998
|
Mochizuki, R., Takeda, A., Sato, N., Kimpara, T., Onodera, H., Itoyama, Y. & Muramatsu, T. Induction of midkine expression in reactive astrocytes following rat transient forebrain ischemia. Exp Neurol, 149, 73-8.
|
|
1998
|
Muramatsu, T. [Recognition of heparin-like domain by midkine and its significance]. Tanpakushitsu Kakusan Koso, 43, 2288-94.
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1998
|
Nakamura, E., Kadomatsu, K., Yuasa, S., Muramatsu, H., Mamiya, T., Nabeshima, T., Fan, Q. W., Ishiguro, K., Igakura, T., Matsubara, S., Kaname, T., Horiba, M., Saito, H. & Muramatsu, T. Disruption of the midkine gene (Mdk) resulted in altered expression of a calcium binding protein in the hippocampus of infant mice and their abnormal behaviour. Genes Cells, 3, 811-22.
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|
1998
|
Obama, H., Biro, S., Tashiro, T., Tsutsui, J., Ozawa, M., Yoshida, H., Tanaka, H. & Muramatsu, T. Myocardial infarction induces expression of midkine, a heparin-binding growth factor with reparative activity. Anticancer Res, 18, 145-52.
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|
1998a
|
Uchimura, K., Muramatsu, H., Kaname, T., Ogawa, H., Yamakawa, T., Fan, Q. W., Mitsuoka, C., Kannagi, R., Habuchi, O., Yokoyama, I., Yamamura, K., Ozaki, T., Nakagawara, A., Kadomatsu, K. & Muramatsu, T. Human N-acetylglucosamine-6-O-sulfotransferase involved in the biosynthesis of 6-sulfo sialyl Lewis X: molecular cloning, chromosomal mapping, and expression in various organs and tumor cells. J Biochem, 124, 670-8.
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1998b
|
Uchimura, K., Muramatsu, H., Kadomatsu, K., Fan, Q. W., Kurosawa, N., Mitsuoka, C., Kannagi, R., Habuchi, O. & Muramatsu, T. Molecular cloning and characterization of an N-acetylglucosamine-6-O-sulfotransferase. J Biol Chem, 273, 22577-83.
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1998c
|
Uchimura, K., Kadomatsu, K., Fan, Q. W., Muramatsu, H., Kurosawa, N., Kaname, T., Yamamura, K., Fukuta, M., Habuchi, O. & Muramatsu, T. Mouse chondroitin 6-sulfotransferase: molecular cloning, characterization and chromosomal mapping. Glycobiology, 8, 489-96.
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|
1998
|
Wang, S., Yoshida, Y., Goto, M., Moritoyo, T., Tsutsui, J., Izumo, S., Sato, E., Muramatsu, T. & Osame, M. Midkine exists in astrocytes in the early stage of cerebral infarction. Brain Res Dev Brain Res, 106, 205-9.
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|
1998
|
Yokota, C., Takahashi, S., Eisaki, A., Asashima, M., Akhter, S., Muramatsu, T. & Kadomatsu, K. Midkine counteracts the activin signal in mesoderm induction and promotes neural formation. J Biochem, 123, 339-46.
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1997
|
Inazumi, T., Tajima, S., Nishikawa, T., Kadomatsu, K., Muramatsu, H. & Muramatsu, T. Expression of the retinoid-inducible polypeptide, midkine, in human epidermal keratinocytes. Arch Dermatol Res, 289, 471-5.
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|
1997
|
Iwasaki, W., Nagata, K., Hatanaka, H., Inui, T., Kimura, T., Muramatsu, T., Yoshida, K., Tasumi, M. & Inagaki, F. Solution structure of midkine, a new heparin-binding growth factor. EMBO J, 16, 6936-46.
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|
1997
|
Kadomatsu, K., Hagihara, M., Akhter, S., Fan, Q. W., Muramatsu, H. & Muramatsu, T. Midkine induces the transformation of NIH3T3 cells. Br J Cancer, 75, 354-9.
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1997
|
Kojima, S., Inui, T., Muramatsu, H., Suzuki, Y., Kadomatsu, K., Yoshizawa, M., Hirose, S., Kimura, T., Sakakibara, S. & Muramatsu, T. Dimerization of midkine by tissue transglutaminase and its functional implication. J Biol Chem, 272, 9410-6.
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1997
|
Koshizawa, S. H., Matsumura, T., Kadono, Y., Sawada, T., Kadomatsu, K., Muramatsu, H. & Muramatsu, T. Alteration of midkine expression associated with chemically-induced differentiation in human neuroblastoma cells. Cancer Lett, 111, 117-25.
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|
1997
|
Mishima, K., Asai, A., Kadomatsu, K., Ino, Y., Nomura, K., Narita, Y., Muramatsu, T. & Kirino, T. Increased expression of midkine during the progression of human astrocytomas. Neurosci Lett, 233, 29-32.
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1997
|
Miyashiro, I., Kaname, T., Shin, E., Wakasugi, E., Monden, T., Takatsuka, Y., Kikkawa, N., Muramatsu, T., Monden, M. & Akiyama, T. Midkine expression in human breast cancers: expression of truncated form. Breast Cancer Res Treat, 43, 1-6.
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|
1997a
|
Nakanishi, T., Kadomatsu, K., Okamoto, T., Tomoda, Y. & Muramatsu, T. Expression of midkine and pleiotropin in ovarian tumors. Obstet Gynecol, 90, 285-90.
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1997b
|
Nakanishi, T., Kadomatsu, K., Okamoto, T., Ichihara-Tanaka, K., Kojima, T., Saito, H., Tomoda, Y. & Muramatsu, T. Expression of syndecan-1 and -3 during embryogenesis of the central nervous system in relation to binding with midkine. J Biochem, 121, 197-205.
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1997
|
Sun, X. Z., Inouye, M., Fukui, Y., Hisano, S., Sawada, K., Muramatsu, H. & Muramatsu, T. An immunohistochemical study of radial glial cells in the mouse brain prenatally exposed to gamma-irradiation. J Neuropathol Exp Neurol, 56, 1339-48.
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1997a
|
Takada, T., Toriyama, K., Muramatsu, H., Song, X. J., Torii, S. & Muramatsu, T. Midkine, a retinoic acid-inducible heparin-binding cytokine in inflammatory responses: chemotactic activity to neutrophils and association with inflammatory synovitis. J Biochem, 122, 453-8.
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1997b
|
Takada, T., Kinkori, T., Muramatsu, H., Hayakawa, A., Torii, S. & Muramatsu, T. Midkine, a retinoic acid-inducible heparin-binding cytokine, is a novel regulator of intracellular calcium in human neutrophils. Biochem Biophys Res Commun, 241, 756-61.
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1997
|
Toriyama, K., Muramatsu, H., Hoshino, T., Torii, S. & Muramatsu, T. Evaluation of heparin-binding growth factors in rescuing morphogenesis of heparitinase-treated mouse embryonic lung explants. Differentiation, 61, 161-7.
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1997
|
Yamada, H., Inazumi, T., Tajima, S., Muramatsu, H. & Muramatsu, T. Stimulation of collagen expression and glycosaminoglycan synthesis by midkine in human skin fibroblasts. Arch Dermatol Res, 289, 429-33.
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|
1997
|
Zhou, H., Muramatsu, T., Halfter, W., Tsim, K. W. & Peng, H. B. A role of midkine in the development of the neuromuscular junction. Mol Cell Neurosci, 10, 56-70.
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|
1996
|
Adachi, Y., Matsubara, S., Pedraza, C., Ozawa, M., Tsutsui, J., Takamatsu, H., Noguchi, H., Akiyama, T. & Muramatsu, T. Midkine as a novel target gene for the Wilms' tumor suppressor gene (WT1). Oncogene, 13, 2197-203.
|
|
1996
|
Inui, T., Bodi, J., Kubo, S., Nishio, H., Kimura, T., Kojima, S., Maruta, H., Muramatsu, T. & Sakakibara, S. Solution synthesis of human midkine, a novel heparin-binding neurotrophic factor consisting of 121 amino acid residues with five disulphide bonds. J Pept Sci, 2, 28-39.
|
|
1996
|
Kaname, T., Kadomatsu, K., Aridome, K., Yamashita, S., Sakamoto, K., Ogawa, M., Muramatsu, T. & Yamamura, K. The expression of truncated MK in human tumors. Biochem Biophys Res Commun, 219, 256-60.
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|
1996
|
Kaneda, N., Talukder, A. H., Nishiyama, H., Koizumi, S. & Muramatsu, T. Midkine, a heparin-binding growth/differentiation factor, exhibits nerve cell adhesion and guidance activity for neurite outgrowth in vitro. J Biochem, 119, 1150-6.
|
|
1996
|
Kojima, T., Katsumi, A., Yamazaki, T., Muramatsu, T., Nagasaka, T., Ohsumi, K. & Saito, H. Human ryudocan from endothelium-like cells binds basic fibroblast growth factor, midkine, and tissue factor pathway inhibitor. J Biol Chem, 271, 5914-20.
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|
1996
|
Miyashiro, I., Kaname, T., Nakayama, T., Nakamori, S., Yagyu, T., Monden, T., Kikkawa, N., Nishisho, I., Muramatsu, T., Monden, M. & Akiyama, T. Expression of truncated midkine in human colorectal cancers. Cancer Lett, 106, 287-91.
|
|
1996
|
Muramatsu, H., Song, X. J., Koide, N., Hada, H., Tsuji, T., Kadomatsu, K., Inui, T., Kimura, T., Sakakibara, S. & Muramatsu, T. Enzyme-linked immunoassay for midkine, and its application to evaluation of midkine levels in developing mouse brain and sera from patients with hepatocellular carcinomas. J Biochem, 119, 1171-5.
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|
1995
|
Aridome, K., Tsutsui, J., Takao, S., Kadomatsu, K., Ozawa, M., Aikou, T. & Muramatsu, T. Increased midkine gene expression in human gastrointestinal cancers. Jpn J Cancer Res, 86, 655-61.
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|
1995a
|
Kojima, S., Muramatsu, H., Amanuma, H. & Muramatsu, T. Midkine enhances fibrinolytic activity of bovine endothelial cells. J Biol Chem, 270, 9590-6.
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|
1995b
|
Kojima, S., Inui, T., Muramatsu, H., Kimura, T., Sakakibara, S. & Muramatsu, T. Midkine is a heat and acid stable polypeptide capable of enhancing plasminogen activator activity and neurite outgrowth extension. Biochem Biophys Res Commun, 216, 574-81.
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1995c
|
Kojima, S., Inui, T., Kimura, T., Sakakibara, S., Muramatsu, H., Amanuma, H., Maruta, H. & Muramatsu, T. Synthetic peptides derived from midkine enhance plasminogen activator activity in bovine aortic endothelial cells. Biochem Biophys Res Commun, 206, 468-73.
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1995
|
Masuda, K., Watanabe, I., Unoki, K., Ohba, N. & Muramatsu, T. Functional Rescue of photoreceptors from the damaging effects of constant light by survival-promoting factors in the rat. Invest Ophthalmol Vis Sci, 36, 2142-6.
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1995a
|
Mitsiadis, T. A., Salmivirta, M., Muramatsu, T., Muramatsu, H., Rauvala, H., Lehtonen, E., Jalkanen, M. & Thesleff, I. Expression of the heparin-binding cytokines, midkine (MK) and HB-GAM (pleiotrophin) is associated with epithelial-mesenchymal interactions during fetal development and organogenesis. Development, 121, 37-51.
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1995b
|
Mitsiadis, T. A., Muramatsu, T., Muramatsu, H. & Thesleff, I. Midkine (MK), a heparin-binding growth/differentiation factor, is regulated by retinoic acid and epithelial-mesenchymal interactions in the developing mouse tooth, and affects cell proliferation and morphogenesis. J Cell Biol, 129, 267-81.
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1995
|
Muramatsu, T. [Midkine in relation to development and pathological status of the nervous system]. Nihon Shinkei Seishin Yakurigaku Zasshi, 15, 275-9.
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|
1995
|
Nakagawara, A., Milbrandt, J., Muramatsu, T., Deuel, T. F., Zhao, H., Cnaan, A. & Brodeur, G. M. Differential expression of pleiotrophin and midkine in advanced neuroblastomas. Cancer Res, 55, 1792-7.
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|
1995
|
Obama, H., Tsutsui, J., Ozawa, M., Yoshida, H., Yoshida, Y., Osame, M. & Muramatsu, T. Midkine (MK) expression in extraembryonic tissues, amniotic fluid, and cerebrospinal fluid during mouse embryogenesis. J Biochem, 118, 88-93.
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|
1995
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Pedraza, C., Matsubara, S. & Muramatsu, T. A retinoic acid-responsive element in human midkine gene. J Biochem, 117, 845-9.
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1995
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Sekiguchi, K., Yokota, C., Asashima, M., Kaname, T., Fan, Q. W., Muramatsu, T. & Kadomatsu, K. Restricted expression of Xenopus midkine gene during early development. J Biochem, 118, 94-100.
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1995
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Unoki, K., Okubo, A., Arimura, H., Uehara, F., Muramatsu, H., Kadomatsu, K. & Muramatsu, T. [Beneficial effect of a retinoic acid responsive gene product, midkine, on constant light-induced retinal damage in albino mice]. Nippon Ganka Gakkai Zasshi, 99, 636-41.
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1995
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Yoshida, Y., Goto, M., Tsutsui, J., Ozawa, M., Sato, E., Osame, M. & Muramatsu, T. Midkine is present in the early stage of cerebral infarct. Brain Res Dev Brain Res, 85, 25-30.
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1994
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Matsubara, S., Take, M., Pedraza, C. & Muramatsu, T. Mapping and characterization of a retinoic acid-responsive enhancer of midkine, a novel heparin-binding growth/differentiation factor with neurotrophic activity. J Biochem, 115, 1088-96.
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1994a
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Matsumoto, K., Wanaka, A., Mori, T., Taguchi, A., Ishii, N., Muramatsu, H., Muramatsu, T. & Tohyama, M. Localization of pleiotrophin and midkine in the postnatal developing cerebellum. Neurosci Lett, 178, 216-20.
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1994b
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Matsumoto, K., Wanaka, A., Takatsuji, K., Muramatsu, H., Muramatsu, T. & Tohyama, M. A novel family of heparin-binding growth factors, pleiotrophin and midkine, is expressed in the developing rat cerebral cortex. Brain Res Dev Brain Res, 79, 229-41.
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1994
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Muramatsu, H., Inui, T., Kimura, T., Sakakibara, S., Song, X. J., Maruta, H. & Muramatsu, T. Localization of heparin-binding, neurite outgrowth and antigenic regions in midkine molecule. Biochem Biophys Res Commun, 203, 1131-9.
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1994
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Obama, H., Matsubara, S., Guenet, J. L. & Muramatsu, T. The midkine (MK) family of growth/differentiation factors: structure of an MK-related sequence in a pseudogene and evolutionary relationships among members of the MK family. J Biochem, 115, 516-22.
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1994
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Take, M., Tsutsui, J., Obama, H., Ozawa, M., Nakayama, T., Maruyama, I., Arima, T. & Muramatsu, T. Identification of nucleolin as a binding protein for midkine (MK) and heparin-binding growth associated molecule (HB-GAM). J Biochem, 116, 1063-8.
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1994
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Unoki, K., Ohba, N., Arimura, H., Muramatsu, H. & Muramatsu, T. Rescue of photoreceptors from the damaging effects of constant light by midkine, a retinoic acid-responsive gene product. Invest Ophthalmol Vis Sci, 35, 4063-8.
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1993
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Fabri, L., Maruta, H., Muramatsu, H., Muramatsu, T., Simpson, R. J., Burgess, A. W. & Nice, E. C. Structural characterisation of native and recombinant forms of the neurotrophic cytokine MK. J Chromatogr, 646, 213-25.
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1993
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Kaname, T., Kuwano, A., Murano, I., Uehara, K., Muramatsu, T. & Kajii, T. Midkine gene (MDK), a gene for prenatal differentiation and neuroregulation, maps to band 11p11.2 by fluorescence in situ hybridization. Genomics, 17, 514-5.
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1993
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Kikuchi, S., Muramatsu, H., Muramatsu, T. & Kim, S. U. Midkine, a novel neurotrophic factor, promotes survival of mesencephalic neurons in culture. Neurosci Lett, 160, 9-12.
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1993
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Maruta, H., Bartlett, P. F., Nurcombe, V., Nur, E. K. M. S., Chomienne, C., Muramatsu, T., Muramatsu, H., Fabri, L., Nice, E. & Burgess, A. W. Midkine (MK), a retinoic acid (RA)-inducible gene product, produced in E. coli acts on neuronal and HL60 leukemia cells. Growth Factors, 8, 119-34.
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1993a
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Michikawa, M., Xu, R. Y., Muramatsu, H., Muramatsu, T. & Kim, S. U. Midkine is a mediator of retinoic acid induced neuronal differentiation of embryonal carcinoma cells. Biochem Biophys Res Commun, 192, 1312-8.
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1993b
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Michikawa, M., Kikuchi, S., Muramatsu, H., Muramatsu, T. & Kim, S. U. Retinoic acid responsive gene product, midkine, has neurotrophic functions for mouse spinal cord and dorsal root ganglion neurons in culture. J Neurosci Res, 35, 530-9.
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1993
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Muramatsu, H., Shirahama, H., Yonezawa, S., Maruta, H. & Muramatsu, T. Midkine, a retinoic acid-inducible growth/differentiation factor: immunochemical evidence for the function and distribution. Dev Biol, 159, 392-402.
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1993a
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Muramatsu, T. Midkine (MK), the product of a retinoic acid responsive gene, and pleiotrophin constitute a new protein family regulating growth and differentiation. Int J Dev Biol, 37, 183-8.
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1993b
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Muramatsu, T. [Midkine (MK): a retinoic acid-responsive, heparin-binding growth factor in relationship with differentiation, development, cancer and neural function]. Seikagaku, 65, 1494-504.
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1993
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Satoh, J., Muramatsu, H., Moretto, G., Muramatsu, T., Chang, H. J., Kim, S. T., Cho, J. M. & Kim, S. U. Midkine that promotes survival of fetal human neurons is produced by fetal human astrocytes in culture. Brain Res Dev Brain Res, 75, 201-5.
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1993
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Tsutsui, J., Kadomatsu, K., Matsubara, S., Nakagawara, A., Hamanoue, M., Takao, S., Shimazu, H., Ohi, Y. & Muramatsu, T. A new family of heparin-binding growth/differentiation factors: increased midkine expression in Wilms' tumor and other human carcinomas. Cancer Res, 53, 1281-5.
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1993
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Yasuhara, O., Muramatsu, H., Kim, S. U., Muramatsu, T., Maruta, H. & Mcgeer, P. L. Midkine, a novel neurotrophic factor, is present in senile plaques of Alzheimer disease. Biochem Biophys Res Commun, 192, 246-51.
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1992
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Nakamoto, M., Matsubara, S., Miyauchi, T., Obama, H., Ozawa, M. & Muramatsu, T. A new family of heparin binding growth/differentiation factors: differential expression of the midkine (MK) and HB-GAM genes during mouse development. J Biochem, 112, 346-9.
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1992
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Simon-Chazottes, D., Matsubara, S., Miyauchi, T., Muramatsu, T. & Guenet, J. L. Chromosomal localization of two cell surface-associated molecules of potential importance in development: midkine (Mdk) and basigin (Bsg). Mamm Genome, 2, 269-71.
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1992
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Uehara, K., Matsubara, S., Kadomatsu, K., Tsutsui, J. & Muramatsu, T. Genomic structure of human midkine (MK), a retinoic acid-responsive growth/differentiation factor. J Biochem, 111, 563-7.
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1991
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Muramatsu, H. & Muramatsu, T. Purification of recombinant midkine and examination of its biological activities: functional comparison of new heparin binding factors. Biochem Biophys Res Commun, 177, 652-8.
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1991
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Tsutsui, J., Uehara, K., Kadomatsu, K., Matsubara, S. & Muramatsu, T. A new family of heparin-binding factors: strong conservation of midkine (MK) sequences between the human and the mouse. Biochem Biophys Res Commun, 176, 792-7.
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1990
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Tomomura, M., Kadomatsu, K., Matsubara, S. & Muramatsu, T. A retinoic acid-responsive gene, MK, found in the teratocarcinoma system. Heterogeneity of the transcript and the nature of the translation product. J Biol Chem, 265, 10765-70.
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