Professor Muramatsu graduated in Science from The University of Tokyo in 1963 and received his PhD (also from The University of Tokyo) in 1968. From 1968-1972 he was Research Fellow, Department of Microbiology and Immunology at the Albert Einstein College of Medicine, New York, USA. He returned to Japan in 1972, first as Assistant Professor (1972-1973) and then as Associate Professor (1973-1980), in the Department of Biochemistry, Kobe University School of Medicine. During that time Prof Muramatsu was also Visiting Scientist, Department of Molecular Biology, Pasteur Institute (1977-1978). He became Professor in the Department of Biochemistry at Kagoshima University Faculty of Medicine in 1980, remaining there until 1993. It was during this time he discovered midkine along with Prof Kadomatsu, publishing the discovery in 1988.
He was then appointed Professor in the Department of Biochemistry, Nagoya University School of Medicine (1993-2000) and then Professor and Chairman, Department of Biological Chemistry, Nagoya University Graduate School of Medicine (2000-2004). He was Professor (2004-2011) and then Visiting Professor (2011-2013), Department of Health Science, Faculty of Psychological and Physical Science, Aichi Gakuin University. He was made Professor Emeritus, Nagoya University in 2004.
Prof Muramatsu has served as Associate Editor, Glycobiology (1999-2007) and President, Japanese Biochemical Society (2002-2003). He received Young Investigator’s Award from Japanese Biochemical Society for research into glycosidases acting on glycoconjugates (1975) and the Chunichi Cultural Prize for the discovery of midkine in 2002. He has over 180 peer-reveiwed publications on midkine alone.